Covid longa: estudo relaciona inflamação e sintomas neuropsiquiátricos

[{"selector":"#anim-714b399b-42ac-4806-acea-b93661e2c067","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b23872d0-1a09-4042-97aa-e6035f0aa259","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-34af724b-0433-4992-a296-04850c975c1f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-61c82f68-c109-40de-8bc3-136d59e086b3","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Andreew Neel/Pexels

[{"selector":"#anim-2e229bdd-f149-4709-8254-c5e5dbcc2a45","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6f871b03-e0a8-45ee-9bb8-51da5cf6d214","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-733cd6f1-d9a5-481d-aa7c-7c85c239231c","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-3d1ea4c1-1b40-42c6-9df6-b9805ab677dd","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-d018c426-c069-4641-bc4c-b5876e3ed3cc [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.812499744007886%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Estudo brasileiro que avaliou pacientes com q u adros moderados ou graves de Covid-19 revelou conexões importantes entre inflamação persistente e desfechos neuropsiquiátricos de longo prazo , como sintomas de ansiedade, depressão e dificuldades cognitivas cottonbro studio/Pexels

[{"selector":"#anim-a019a025-9d23-4e6e-a233-2961dc765652","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d2785670-e5ac-499e-aa32-062683a9ceb4","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-fceed0ad-7a39-49aa-af7e-f4d2ef19d89a","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-1810deb8-5563-4155-b625-8c17db1da923","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] A investigação explorou o impacto de citocinas e quimiocinas – proteínas que controlam a resposta imunológica do corpo – nos sintomas neuropsiquiátricos . O estudo acompanhou 108 participantes por um período de dois anos após alta hospitalar por Covid-19 Engin Akyurt/Pexels

[{"selector":"#anim-2578014c-512c-4894-9fdf-bc9ba3350380","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1f3b6efe-4e0f-43fe-9a0d-0a2d49bed6d5","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1eaa27d4-bac0-417b-b378-9017b76fbc58","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-6b47aacb-0ed5-49c2-b59b-af019af07211","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-d82f59f5-4032-45fd-8676-324e6d87e40f [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(-7.724609118474579%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] Os pesquisadores identificaram que níveis elevados de eotaxina, um marcador inflamatório associado à neurodegeneração, estavam ligados aos sintomas depressivos Ketut Subiyanto/Pexels

[{"selector":"#anim-243bb671-b4f9-48e2-ae08-23c25962a6f8","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-237e22df-6e08-4c6f-91b6-be2abd916e6f","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-5d4ae3c3-69cc-4e28-bb41-f8e8eccc09b5","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-7e6417be-ab9d-4c9a-a8ee-4023c5d66add","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Os cientistas avaliaram também o fator de crescimento vascular endotelial (VEGF), percebendo associação com a ansiedade e apontando-o como um conector importante em modelos analíticos Andrea Piacquadio/Pexels

[{"selector":"#anim-5e103eb3-23ae-4678-97db-7e7e07cdacc2","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9b5a4055-2aed-47c7-afa2-1cf9e59eda06","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-af8845a5-d77f-4757-bd02-04b5bb0dd17f","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-7012f4e6-89a7-4dd8-ae19-f07eab21159e","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-d6f95c68-3f3c-4960-9875-b7fda22f0734 [data-leaf-element=\"true\"]","keyframes":{"transform":["translate3d(7.816123165828376%, 0, 0)","translate3d(0%, 0, 0)"]},"delay":0,"duration":2000,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] “Os achados destacam a complexidade dessas interações e sugerem que esses biomarcadores podem servir como ferramentas de diagnóstico e prognóstico para a síndrome de Covid longa”, destaca Felipe Couto, graduando na Faculdade de Medicina da Universidade de São Paulo cottonbro studio/Pexels

[{"selector":"#anim-d7aa41c6-0116-4343-a4b0-667c0b99ce63","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d9b47c74-fc2c-4ee2-a3e3-7bf0b54b07c1","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bffa286e-2704-4e38-b197-21a7e9e73486","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-4b768c8a-7d1e-47dd-a9a9-b72b66752d96","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Os dados obtidos na investigação científica reforçam o papel da inflamação na persistência dos sintomas neuropsiquiátricos pós-Covid, o que contribui para um avanço no entendimento dessa condição debilitante Alex Green/Pexels

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[{"selector":"#anim-00c95269-cd52-4ced-a361-03c1db4d945c","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-4c15b145-fec4-46fe-aa5f-069b1d607f82","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-937df941-8d12-48a2-996d-21f327bb1ff9","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-33059bf2-6c4c-4034-b5be-d4820e32ba27","keyframes":{"transform":["translate3d(0px, 2132.63615%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-96a6d886-f65b-46aa-9ecc-4e67abf78d96","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-15f81380-3dbc-431f-bd23-474b4d7693dc","keyframes":{"transform":["translate3d(-117.84387%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bc00cf7a-ef10-4584-8ea1-ad648b160636","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-161b72db-d7ef-4ffe-be84-bcee09f5cc5b","keyframes":{"transform":["translate3d(0px, 870.06218%, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Liza Summer/Pexels leia mais em