Nova vacina tem resultados promissores contra câncer renal avançado

[{"selector":"#anim-5dc3498c-6d28-4d59-b7f3-d43fc424baa0","keyframes":{"opacity":[0,1]},"delay":0,"duration":1000,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-deaf9064-5653-4d6e-ae8e-8abc2140fea7","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-6a750515-6013-4e2b-8a93-9a1007dd0579","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] [{"selector":"#anim-8c0dbf2d-3a13-4df0-8ea7-076ea1709a86","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] Pexels

[{"selector":"#anim-69e1eab0-7f7c-4717-bad1-c1c9b77d3bf7","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b7e8e528-3c43-4933-b0a8-58f1cdcfb2c3","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-995a89ba-82ba-4257-a2ea-081f5b26a45d","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-14339c2c-8182-473a-bd6a-09c35b721515","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Uma nova vacina personalizada contra o câncer mostrou resultados promissores em pacientes com câncer renal avançado REUTERS/Eric Gaillard

[{"selector":"#anim-9f5a6ce1-6af3-43e6-966d-fce87212d2ca","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-14567db6-9584-420a-9de2-2dc2a56ad113","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-9fc4981a-7be0-427a-a5cf-be927dd147dc","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c9567d09-1ee4-4cfb-83c7-dfedd9211857","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Em artigo publicado na revista científica Nature, pesquisadores mostraram que todos os participantes de um ensaio clínico geraram uma resposta imune anticâncer bem-sucedida após receber o tratamento Tomaz Silva/Agência Brasil

[{"selector":"#anim-271dea67-1307-4fdd-b631-b688b12349bb","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-98d981e1-39c7-4c68-a16a-44e7c6df71ab","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-30a8cced-e190-4969-b046-84a82cce37cc","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-b1cf1a69-2b37-4b76-acb9-f6b5703b4c8f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Segundo o artigo, as vacinas foram administradas após a cirurgia de remoção do tumor e são projetadas para treinar o sistema imunológico a reconhecer e eliminar células tumorais restantes Thanasis/GettyImages

[{"selector":"#anim-a25e9b85-1c35-4e16-bf95-25a862b76ba9","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-bf0d418d-03b4-40be-86d1-7e853a72445d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-2604de36-cd6b-42c6-be6b-5b44363e9fb9","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-39f2f306-9b0b-4784-991e-a2d26d12a66f","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] A cirurgia é o tratamento padrão para pacientes com carcinoma renal de células claras, um tipo de câncer renal, em estágio III ou IV. O procedimento pode ser seguido por imunoterapia com pembrolizumabe, um inibidor de ponto de verificação imunológico Pixabay

[{"selector":"#anim-1ff3dff7-6b7d-4ed0-9d06-320aae572694","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e0077674-7844-4eb9-b171-d2ad7df2002a","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-6174d9bc-5659-472c-a9ae-36a138fbb04a","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-c7246551-23bf-4477-994a-d411e9705f1a","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] O pembrolizumabe induz uma resposta imunológico que reduz o risco de o câncer voltar. No entanto, cerca de dois terços dos pacientes podem sofrer recidivas (retorno do tumor) e têm opções de tratamentos limitadas Freepick

[{"selector":"#anim-c191d221-bee4-4f90-8583-7b328947e44a","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-1ec12dc4-8a04-4480-924c-6a199f43910b","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c574b6fc-0239-4995-b052-6f6761ad6990","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-63ba35e8-e646-477f-9c54-77835b286f22","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Por isso, os pesquisadores decidiram investigar novas formas de combater esse tipo de câncer. No ensaio clínico, eles trataram nove pacientes com carcinoma de células renais claras em estágio III ou IV com uma vacina contra câncer personalizada após a cirurgia Pexels/Nataliya Vaitkevich

[{"selector":"#anim-213dd73e-4236-42d6-9c71-2f59b91a3643","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-66186edc-61c6-4cfe-85c5-b8ec7a46999d","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-c1c3de00-2e42-448e-b18f-ab1f14d8a1d2","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-ee07ed11-8c2c-4d31-9c4f-555684578502","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Vacinas personalizadas são aquelas desenvolvidas para reconhecer o câncer individual de um paciente a partir do tecido tumoral removido durante cirurgia. A equipe de pesquisadores extrai características moleculares das células tumorais A. Martin UW Photography/Getty Images

[{"selector":"#anim-59f87d66-4db1-436e-ad0d-dcd8c5feeaaf","keyframes":{"opacity":[0,1]},"delay":0,"duration":1500,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-a7a0dba0-0818-4e10-981a-92c381cb9fc9","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.4, 0.4, 0.0, 1)","fill":"both"}] [{"selector":"#anim-187323c8-2937-46a2-bd81-d6373158f2ad","keyframes":{"opacity":[0,1]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"both"}] [{"selector":"#anim-2e0e7d34-b076-4765-a63b-adc1983b449b","keyframes":{"transform":["scale(0.3333333333333333)","scale(1)"]},"delay":0,"duration":500,"easing":"cubic-bezier(.3,0,.55,1)","fill":"forwards"}] Por meio de uma série de análises, a equipe descobriu que a vacina induziu uma resposta imune em três semanas. Ensaios clínicos com um número maior de pacientes são necessários para confirmar a eficácia da vacina e explorar seu potencial total no combate ao câncer Photo By: Kaboompics.com/Pexels

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